SynInnova Laboratories Inc.

SI-5488

PF-5274857 hydrochloride, >98% (HPLC)

CAS No. :

[1613439-62-5]

MDL No. :

MFCD24387542

Synonyms : 1-(4-(5’-Chloro-3,5-dimethyl-[2,4'-bipyridin]-2'-yl)piperazin-1-yl)-3-(methylsulfonyl)propan-1-one hydrochloride

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
10MG	180.00	- +	Back Order	Estimated to Ship on 06.08.2024
50MG	780.00	- +	Back Order	Estimated to Ship on 06.08.2024
100MG	1480.00	- +	Back Order	Estimated to Ship on 06.08.2024
250MG	2480.00	- +	Back Order	Estimated to Ship on 06.08.2024

Chemical Properties
Mol. Formula : C₂₀H₂₅ClN₄O₃S . HCl	Mol. Weight : 473.41
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PF-5274857 hydrochloride is a potent, selective, orally active and brain-penetrant antagonist of SMO, with an IC50 of 5.8 nM and Ki of 4.6 nM. PF-5274857 hydrochloride has potential for research of tumor types including brain tumors and brain metastasis driven by an activated Hh pathway.

References : Rohner A. et al.: Mol Cancer Ther., 11(1), 57-65, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5488

Product Name : PF-5274857 hydrochloride

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Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

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SI-5488

PF-5274857 hydrochloride, >98% (HPLC)

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