SynInnova Laboratories Inc.

SI-5516

DBPR112, >98% (HPLC)

CAS No. :

[1226549-49-0]

Synonyms : (S)-4-(Dimethylamino)-N-(3-(4-((2-hydroxy-1-phenylethyl)amino)-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl)butanamide

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	450.00	- +	Back Order	Estimated to Ship on 06.07.2024
10MG	800.00	- +	Back Order	Estimated to Ship on 06.07.2024
25MG	1650.00	- +	Back Order	Estimated to Ship on 06.07.2024
50MG	2450.00	- +	Back Order	Estimated to Ship on 06.07.2024
100MG	3650.00	- +	Back Order	Estimated to Ship on 06.07.2024

Chemical Properties
Mol. Formula : C₃₂H₃₃N₅O₃	Mol. Weight : 535.65
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : DBPR112 is an orally active furanopyrimidine-based EGFR inhibitor with IC50s of 15 nM and 48 nM for EGFRWT and EGFRL858R/T790M, respectively. DBPR112 can occupy the ATP-binding site. DBPR112 has significant antitumor efficacy.

References : Lin S. Y. et al.: J. Med Chem., 62(22), 10108-10123, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5516

Product Name : DBPR112

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SI-5516

DBPR112, >98% (HPLC)

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