SynInnova Laboratories Inc.

SI-5532

DSM 265, >98% (HPLC)

CAS No. :

[1282041-94-4]

MDL No. :

MFCD28502125

Synonyms : 2-(1,1-Difluoroethyl)-5-methyl-N-(4-(pentafluoro-λ6-sulfaneyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
25MG	150.00	- +	Back Order	Estimated to Ship on 06.13.2024
50MG	250.00	- +	Back Order	Estimated to Ship on 06.13.2024
100MG	450.00	- +	Back Order	Estimated to Ship on 06.13.2024
250MG	950.00	- +	Back Order	Estimated to Ship on 06.13.2024
500MG	1750.00	- +	Back Order	Estimated to Ship on 06.13.2024

Chemical Properties
Mol. Formula : C₁₄H₁₂F₇N₅S	Mol. Weight : 415.33
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : DSM265 is a long-duration inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 of 8.9 nM. DSM265 can also inhibit the growth of Pf3D7 parasites with an EC50 of 4.3 nM.

References : Kokkonda S. et al.: J. Med Chem., 59(11), 5416-31, 2016; Phillips M. A. et al.: Sci Transl Med., 7(296), 296ra111, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5532

Product Name : DSM 265

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SI-5532

DSM 265, >98% (HPLC)

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