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SI-5586

Ulixertinib, >98% (HPLC)

CAS No. : 
[869886-67-9]    
MDL No. : 
MFCD22628898
Synonyms : (S)-4-(5-Chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide; BVD-523; VRT752271

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG70.00
-
+
Back Order Estimated to Ship on 05.20.2024
10MG110.00
-
+
Back Order Estimated to Ship on 05.20.2024
50MG250.00
-
+
Back Order Estimated to Ship on 05.20.2024
100MG450.00
-
+
Back Order Estimated to Ship on 05.20.2024
250MG650.00
-
+
Back Order Estimated to Ship on 05.20.2024
Chemical Properties
C21H22Cl2N4O2 433.33
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Ulixertinib is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line.
References : Ward R. A. et al.: J Med Chem., 58(11), 4790-801, 2015; Kumar R. et al.: J. Pharm Biomed Anal., 125, 140-4, 2016; Ning C. et al.: Oncotarget., 8(27), 44295-44311, 2017.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5586

Product Name : Ulixertinib

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