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SI-5660

GTS-21 dihydrochloride, >98% (HPLC)

CAS No. : 
[156223-05-1]    
MDL No. : 
MFCD00941364
Synonyms : (E)-3-(2,4-Dimethoxybenzylidene)-3,4,5,6-tetrahydro-2,3'-bipyridine dihydrochloride

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG70.00 Back Order Estimated to Ship on 06.06.2024
25MG120.00 Back Order Estimated to Ship on 06.06.2024
50MG150.00 Back Order Estimated to Ship on 06.06.2024
100MG230.00 Back Order Estimated to Ship on 06.06.2024
250MG350.00 Back Order Estimated to Ship on 06.06.2024
Chemical Properties
C19H20N2O2 . 2HCl 381.30
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : GTS-21 dihydrochloride is a selective alpha7 nicotinic acetylcholine receptor (α7-nAChR) agonist with anti‑inflammatory and cognition‑enhancing activities. GTS-21 dihydrochloride is also a α4β2 (Ki=20 nM for humanα4β2) and 5-HT3A receptor (IC50=3.1 μM) antagonist.
References : Briggs C. A. et al.: Pharmacol Biochem Behav., 57(1-2), 231-241, 1997; Zhang R. et al.: J. Pharmacol Exp Ther., 317(3), 1276-1284, 2006; Mei Z. et al.: Oncol Rep., 40(4), 2287-2297, 2018.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5660

Product Name : GTS-21 dihydrochloride

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