[1795142-30-1]    

Synonyms : (E)-N-(3-(Methyl-d₃)-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide-d₃

Applications : Methazolamide-d6 the deuterium labelled version analog of Methazolamide, which is a sulfonamide derivative used as a carbonic anhydrase inhibitor with a Ki of 14 nM for human carbonic anhydrase II. Methazolamide, an intraocular pressure-lowering agent, reduces intraocular pressure elevations associated with glaucoma and other ocular disorders.

References : Yang F. et al.: Pharmacogenomics J. 16(1), 83-87, 2016; Abbate F. et al.: J. Enzyme Inhib Med Chem., 18(4), 303-308, 2003.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.