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SL-2248 

Dihydrodiol Ibrutinib, 98%

CAS No. : 
[1226872-27-0]    
Synonyms : 1-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one; PCI 45227

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG180.00 In Stock Estimated to Ship on 05.23.2024
10MG350.00 In Stock Estimated to Ship on 05.23.2024
25MG800.00 In Stock Estimated to Ship on 05.23.2024
50MG1500.00 In Stock Estimated to Ship on 05.23.2024
Chemical Properties
C25H26N6O4 474.51
Off-white solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Dihydrodiol Ibrutinib is a metabolite of Ibrutinib, which is a selective, irreversible Btk inhibitor with IC50 value of 0.5 nM.
References : Honigberg L. A. et al.: Proc. Nat. Acad. Sci., U S A. 107 (29),13075-13080, 2010; Herman S.E. et al.: Blood. 117 (23), 6287-6296, 2011; Chang B.Y. et al.: Arthritis Res Ther., 13(4), R115, 2011; Wu H. et al.: Sci Rep., 7 (1), 466, 2017.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-2248

Product Name : Dihydrodiol Ibrutinib

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