SynInnova Laboratories Inc.

SL-3745

Pemetrexed-5-methyl ester, 98%

CAS No. :

[1265908-60-8]

Synonyms : (S)-2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanoic acid; Pemetrexed impurity 1

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
10MG	120.00	- +	Back Order	Estimated to Ship on 05.27.2024
50MG	580.00	- +	Back Order	Estimated to Ship on 05.27.2024
100MG	980.00	- +	Back Order	Estimated to Ship on 05.27.2024

Chemical Properties
Mol. Formula : C₂₁H₂₃N₅O₆	Mol. Weight : 441.44
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Pemetrexed-5-methyl ester is an impurity of Pemetrexed, which is a novel antifolate and antimetabolite for dihydrofolate reductase-thymidylate synthase (DHFR-TS). It is used to treat for pleural mesothelioma (cancer of the outer covering of the lungs) non small cell lung cancer (NSCLC).

References : Shih C. et al.: Cancer Res., 57(6), 1116-1123, 1997; Iwahori K. et al.: Int J. Cancer., 132(2), 459-471, 2013; Teicher B. A. et al.: Clin. Cancer Res. , 6(3), 1016-1023, 2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-3745

Product Name : Pemetrexed-5-methyl ester

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SL-3745

Pemetrexed-5-methyl ester, 98%

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