Synonyms : Sodium hydrogen (4-amino-1-hydroxy-1-phosphonobutyl-d₆)phosphonate; G-704650-d₆, MK-217-d₆

Applications : Alendronate-d6 sodium trihydrate is a deuterium labelled version of Alendronic acid, which is a nitrogen-containing, second generation bisphosphonate used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.

References : Fisher J. E. et al.: Proc Natl Acad Sci U S A, 96(1), 133-138, 1999; Bergstrom J. D. et al. Arch Biochem Biophys, 373(1), 231-241, 2000; Keller R. K. et al.: Biochem Biophys Res Commun, 266(2), 560-563, 1999;
Elliott S. N. et al.: Life Sci, 62(1), 77-91, 1998; Stearns M. E. et al.: Invasion Metastasis, 16(3), 116-131, 1996.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.