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SL-5941

(R)-3-Hydroxy midostaurin-d5, >98% (CP)

Isotopic Purity : 
98 atom % D
Related CAS No. : 
[155848-20-7] of the unlabelled compound.
Synonyms : (R)-CGP 52421-d5

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG2980.00
-
+
Back Order Estimated to Ship on 06.04.2024
10MG4980.00
-
+
Back Order Estimated to Ship on 06.04.2024
Chemical Properties
C35H25D5N4O5 591.68
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : (R)-3-Hydroxy midostaurin-d5 is a deuterium labelled version of (R)-3-Hydroxy midostaurin, a potent kinases inhibitor. (R)-3-Hydroxy midostaurin is a major metabolite of Midostaurin, undergoing by the hepatic CYP3A4 enzyme. (R)-3-Hydroxy midostaurin has the potential for acute myeloid leukemia (AML).
References : Fabbro D. et al.: Pharmacol Ther., 82(2-3), 293-301, 1999; Ikegami Y. et al.: Jpn. J. Pharmacol., 70(1), 65-72, 1996; Manley P. W. et al.: Biochemistry 57(38) 5576-5590, 2018.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-5941

Product Name : (R)-3-Hydroxy midostaurin-d5

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