SynInnova Laboratories Inc.

SI-5670

PNU-120596, >98% (HPLC)

CAS No. :

[501925-31-1]

MDL No. :

MFCD00095313

Synonyms : 1-(5-Chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea; NSC 216666

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
25MG	120.00	- +	Back Order	Estimated to Ship on 05.31.2024
50MG	220.00	- +	Back Order	Estimated to Ship on 05.31.2024
100MG	380.00	- +	Back Order	Estimated to Ship on 05.31.2024
250MG	680.00	- +	Back Order	Estimated to Ship on 05.31.2024
500MG	1280.00	- +	Back Order	Estimated to Ship on 05.31.2024

Chemical Properties
Mol. Formula : C₁₃H₁₄ClN₃O₄	Mol. Weight : 311.72
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PNU-120596 is a potent and selective α7 nAChR positive allosteric modulator (PAM) with an EC50 of 216 nM. PNU-120596 is inactive against α4β2, α3β4, and α9α10 nAChRs. PNU-120596 has the potential for psychiatric and neurological disorders research.

References : Hurst R. S. et al.: J. Neurosci., 25(17), 4396-4405, 2005; Barron S. C. et al.: Mol Pharmacol., 76(2), 253-263, 2009; Munro G. et al.: Br. J. Pharmacol., 167(2), 421-35, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5670

Product Name : PNU-120596

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