SynInnova Laboratories Inc.

SI-5693

B026, >98% (HPLC)

Synonyms : (S)-1-(2-((S)-7-Fluoro-3-(trifluoromethyl)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)-2-oxoethyl)-5'-(1-methyl-1H-pyrazol-4-yl)-2',3'-dihydrospiro[imidazolidine-4,1'-indene]-2,5-dione

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	Request Quote	- +	Back Order	Estimated to Ship on 05.29.2024
25MG	Request Quote	- +	Back Order	Estimated to Ship on 05.29.2024
100MG	Request Quote	- +	Back Order	Estimated to Ship on 05.29.2024
250MG	Request Quote	- +	Back Order	Estimated to Ship on 05.29.2024
500MG	Request Quote	- +	Back Order	Estimated to Ship on 05.29.2024

Note: B026 is not in stock, can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the following Bulk Quote Request. We respond promptly. Thank You!

Chemical Properties
Mol. Formula : C₂₇H₂₃F₄N₅O₄	Mol. Weight : 557.51
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : B026 is a novel, highly selective, potent inhibitor of p300/CBP histone acetyltransferases (HAT) with IC50 values of 1.8 nM to p300 and 9.5 nM to CBP enzyme inhibitory activity. Moreover, B026 achieves significant and dose-dependent tumor growth inhibition in an animal model of human cancer. B026 is a potential clinical development candidate.

References : Yang. Y. et al.: J. Med. Chem., 63(3), 1337-1360, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

To receive price and delivery information on larger quantities, please complete the form below and we will respond promptly.

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Your request for quote will also be accepted by e-mail at sales@syninnova.com or Fax: +1 780 485 2963.

Product ID : SI-5693

Product Name : B026

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

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SI-5693

B026, >98% (HPLC)

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