SynInnova Laboratories Inc.

SI-5145

PH-797804, >98% (HPLC)

CAS No. :

[586379-66-0]

MDL No. :

MFCD18251426

Synonyms : 3-(3-Bromo-4-((2,4-difluorobenzyl)oxy)-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	90.00	- +	Back Order	Estimated to Ship on 05.31.2024
10MG	180.00	- +	Back Order	Estimated to Ship on 05.31.2024
25MG	350.00	- +	Back Order	Estimated to Ship on 05.31.2024
50MG	550.00	- +	Back Order	Estimated to Ship on 05.31.2024
250MG	950.00	- +	Back Order	Estimated to Ship on 05.31.2024

Chemical Properties
Mol. Formula : C₂₂H₁₉BrF₂N₂O₃	Mol. Weight : 477.31
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PH-797804 is a ATP-competitive, selective p38α/p38β inhibitor (IC50=26 nM and Ki=5.8 nM for p38α; Ki=40 nM for p38β) and does not inhibit JNK2. PH-797804 has met safety criteria in human phase I studies and is under clinical development for several inflammatory conditions.

References : Hope H. R. et al.: J Pharmacol Exp Ther., 331(3), 882-895, 2009; Xing L. et al.: Biochemistry 48(27), 6402-6411, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5145

Product Name : PH-797804

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SI-5145

PH-797804, >98% (HPLC)

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