SynInnova Laboratories Inc.

SL-2475

Apremilast EP impurity B, 98%

CAS No. :

[15371-06-9]

MDL No. :

MFCD00612509

Synonyms : 3-Acetamidophthalic acid

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	100.00	- +	Back Order	Estimated to Ship on 05.16.2024
25MG	300.00	- +	Back Order	Estimated to Ship on 05.16.2024
100MG	880.00	- +	Back Order	Estimated to Ship on 05.16.2024

Chemical Properties
Mol. Formula : C₁₀H₉NO₅	Mol. Weight : 223.18
Appearance : Pale yellow solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : 3-Acetamidophthalic acid is an impurity of Apremilast (Apremilast EP impurity B). A novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors. Apremilast inhibits PDE4 with an IC₅₀ of 74 nM using 1 μM cAMP as substrate.

References : Perez-Aso M. et al.: Arthritis Res Ther.,17, 249, 2015; Chen L.G. et al.: J. Chromatogr Sci. 54 (8), 1336-40, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-2475

Product Name : Apremilast EP impurity B

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