SynInnova Laboratories Inc.

SI-5259

Glasdegib, >98% (HPLC)

CAS No. :

[1095173-27-5]

MDL No. :

MFCD25976839

Synonyms : 1-((2R,4R)-2-(1H-Benzo[d]imidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea; PF-04449913

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	80.00	- +	Back Order	Estimated to Ship on 06.15.2024
10MG	150.00	- +	Back Order	Estimated to Ship on 06.15.2024
25MG	350.00	- +	Back Order	Estimated to Ship on 06.15.2024
50MG	550.00	- +	Back Order	Estimated to Ship on 06.15.2024
100MG	950.00	- +	Back Order	Estimated to Ship on 06.15.2024

Chemical Properties
Mol. Formula : C₂₁H₂₂N₆O	Mol. Weight : 374.45
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Glasdegib is a potent and orally bioavailable smoothened inhibitor. Glasdegib binds to human SMO (amino acids 181-787) with an IC50 of 4 nM. Glasdegib is used for the treatment of newly-diagnosed acute myeloid leukemia (AML).

References : Sadarangani A. et al. J. Transl Med. Mar 21, 13, 98, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5259

Product Name : Glasdegib

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