SynInnova Laboratories Inc.

SI-5260

Glasdegib maleate, >98% (HPLC)

CAS No. :

[2030410-25-2]

Synonyms : 1-((2R,4R)-2-(1H-Benzo[d]imidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea maleate; PF-04449913 maleate

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	80.00	- +	Back Order	Estimated to Ship on 06.02.2024
10MG	150.00	- +	Back Order	Estimated to Ship on 06.02.2024
25MG	350.00	- +	Back Order	Estimated to Ship on 06.02.2024
50MG	650.00	- +	Back Order	Estimated to Ship on 06.02.2024
100MG	1250.00	- +	Back Order	Estimated to Ship on 06.02.2024

Chemical Properties
Mol. Formula : C₂₁H₂₂N₆O . C₄H₄O₄	Mol. Weight : 490.52
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Glasdegib maleate is a potent and orally bioavailable smoothened inhibitor. Glasdegib binds to human SMO (amino acids 181-787) with an IC50 of 4 nM.Glasdegib is used for the treatment of newly-diagnosed acute myeloid leukemia (AML).

References : Sadarangani A. et al. J. Transl Med. Mar 21, 13, 98, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5260

Product Name : Glasdegib maleate

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SI-5260

Glasdegib maleate, >98% (HPLC)

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