SynInnova Laboratories Inc.

SI-5527

PD318088, >98% (HPLC)

CAS No. :

[391210-00-7]

MDL No. :

MFCD18384973

Synonyms : 5-Bromo-N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	130.00	- +	Back Order	Estimated to Ship on 06.09.2024
10MG	230.00	- +	Back Order	Estimated to Ship on 06.09.2024
25MG	450.00	- +	Back Order	Estimated to Ship on 06.09.2024
50MG	750.00	- +	Back Order	Estimated to Ship on 06.09.2024
100MG	950.00	- +	Back Order	Estimated to Ship on 06.09.2024

Chemical Properties
Mol. Formula : C₁₆H₁₃BrF₃IN₂O₄	Mol. Weight : 561.09
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PD318088 is a potent, allosteric and non-ATP competitive MEK1/2 inhibitor, an analog of PD184352. PD318088 binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site. PD318088 can be used for cancer research.

References : Ohren J. F. et al.: Nat Struct Mol Biol., 11(12), 1192-7, 2004; Han S. et al.: Bioorg Med Chem Lett., 15(24), 5467-73, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5527

Product Name : PD318088

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