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SI-5528

CI-1040, >98% (HPLC)

CAS No. : 
[212631-79-3]    
MDL No. : 
MFCD02683961
Synonyms : 2-((2-Chloro-4-iodophenyl)amino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide; PD184352

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG70.00 Back Order Estimated to Ship on 05.31.2024
25MG150.00 Back Order Estimated to Ship on 05.31.2024
50MG220.00 Back Order Estimated to Ship on 05.31.2024
100MG350.00 Back Order Estimated to Ship on 05.31.2024
250MG550.00 Back Order Estimated to Ship on 05.31.2024
Chemical Properties
C17H14ClF2IN2O2 478.66
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : CI-1040 is an orally active, highly specific, small-molecule inhibitor of MEK with an IC50 of 17 nM for MEK1. CI-1040 is developing for potential treatment of breast cancer and other cancers.
References : Allen L. F. et al.: Semin Oncol., 30(5 Suppl 16), 105-16, 2003; Wei C. R. et al.: Eur Rev Med Pharmacol Sci., 20(10), 1961-8, 2016; Kramer B. W. et al.: BMC Cancer., 4, 24, 2004.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5528

Product Name : CI-1040

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