SynInnova Laboratories Inc.

SL-2584

Bosentan-13C2, d4, >99% (HPLC)

Isotopic Purity :

98 atom % D and 99 atom % 13C

Related CAS No. :

[150726-52-6] of the unlabelled compound

Synonyms : 4-(tert-Butyl)-N-(6-(2-hydroxyethoxy-13C2, d4)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide; Benzenesulfonamide-13C2, d4; Tracleer-13C2 d4; Actelion-13C2, d4; Ro 47-0203/039-13C, d4; Ro 47-0203-13C, d4

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	880.00	- +	In Stock	Estimated to Ship on 05.12.2024
10MG	1680.00	- +	In Stock	Estimated to Ship on 05.12.2024

Chemical Properties
Mol. Formula : C₂₅¹³C₂H₂₅D₄N₅O₆S	Mol. Weight : 557.62
Appearance : Light yellow solid	Melting Point : Not available
Solubility : DCM, MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : Bosentan-13C2, d4 is a mixed labelled analog, which is a competitive and dual antagonist of endothelin-1 (ET) for the ET_Aand ET_B receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively.

References : Dhillon S. et al.: Am J. Cardiovasc Drugs 9 (5), 331-350, 2009; Akamata K. et al. Arthritis Res Ther. 16 (2), R86, 2014; Iglarz M. et al. Life Sci. 118 (2), 333-339, 2014; Son G. Y. et al. PLoS One 11(12), e0167713, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-2584

Product Name : Bosentan-13C2, d4

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SL-2584

Bosentan-13C2, d4, >99% (HPLC)

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