SynInnova Laboratories Inc.

SL-2482

Apremilast impurity 2, 98%

CAS No. :

[6296-53-3]

MDL No. :

MFCD00453138

Synonyms : N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide; 3-Acetylaminophthalic anhydride

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
1G	120.00	- +	Back Order	Estimated to Ship on 05.13.2024
10G	980.00	- +	Back Order	Estimated to Ship on 05.13.2024

Chemical Properties
Mol. Formula : C₁₀H₇NO₄	Mol. Weight : 205.17
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : 3-Acetylaminophthalic anhydride an impurity of Apremilast. A novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors. Apremilast inhibits PDE4 with an IC₅₀of 74 nM using 1 μM cAMP as substrate.

References : Perez-Aso M. et al.: Arthritis Res Ther.,17, 249, 2015; Chen L.G. et al.: J. Chromatogr Sci. 54 (8), 1336-40, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-2482

Product Name : Apremilast impurity 2

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SL-2482

Apremilast impurity 2, 98%

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